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Sangamo Therapeutics, Inc.: Sangamo Announces EMA Releases Details Supporting Orphan Designation for BIVV003 for the Treatment of Sickle Cell Disease


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Sangamo Therapeutics, Inc. (Nasdaq: SGMO), a genomic medicine company, today announced that the European Medicines Agency s Committee for Orphan Medicinal Products (COMP) released details supporting the Orphan Designation of BIVV003, an investigational
ex vivo gene-edited cell therapy product candidate currently being evaluated for the treatment of sickle cell disease in the Phase 1/2 PRECIZN-1 study partnered with Sanofi. The Committee s decision to grant Orphan Designation was based in part on early data from three patients that had 52 weeks, 13 weeks, and 29 days of follow-up, respectively.
In recently published minutes, the Committee considered the preliminary clinical observations of BIVV003 as well as the potential of long-term effects that may obviate the need for frequent treatment suggested a clinically relevant advantage. The Committee s published minutes report information on select patient characteristics for the first three patients treated, includin ....

Aaron Feingold , Exchange Commission , Sangamo Therapeutics Inc , Sangamo Therapeutics , European Medicines Agency , Orphan Medicinal Products , Orphan Designation , Annual Report , ஆரோன் பேன்கோல்த் , பரிமாற்றம் தரகு , சங்கமோ சிகிச்சை இன்க் , சங்கமோ சிகிச்சை , ஆர்ஃபந் மருத்துவ ப்ராடக்ட்ஸ் , ஆர்ஃபந் பதவி , ஆண்டு அறிக்கை ,

Novartis International AG: Novartis and the Bill & Melinda Gates Foundation collaborate to discover and develop an accessible in vivo gene therapy for sickle cell disease


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Project brings together Novartis drug discovery and gene therapy expertise and funding support from the Gates Foundation
Agreement aims to address disparity in access to treatments and to prioritize populations and regions that bear the
greatest burden
of sickle cell disease in the search for curative therapies
Effort expands on Novartis commitment to sickle cell disease, which includes a therapeutic pipeline and a holistic approach to diagnosis, treatment, and management of the disease in sub-Saharan Africa
Basel, February 17, 2021 - Novartis today announced that it has entered into a grant agreement with the Bill & Melinda Gates Foundation. As part of the agreement, the foundation will provide funding support for the discovery and development of a single-administration, ....

United States , Isabella Zinck , Jay Bradner , Thomas Hungerbuehler , Kara Cournoyer , Samir Shah , Lutz Hegemann , Jamie Bennett , Sloan Simpson , Katerina Kontzalis , Antonio Ligi , Trevor Mundel , Novartis Institutes For Biomedical Research , National Institutes Of Health , Melinda Gates Foundation , Global Health Cr Communications , Novartis Us External Communications , Novartis External Communications , Exchange Commission , Us National Library Of Medicine , Global Health , Gates Foundation , Melinda Gates , Novartis Institutes , Biomedical Research , Saharan Africa ,

Sugu of 'Sugu Pavithra' YouTube channel pleads guilty to possessing sickle at hospital


IPOH: M. Sugu (
pic) has pleaded guilty to a charge of possessing a sickle at Hospital Raja Permaisuri Bainun in July last year.
Sugu – one half of the “Sugu Pavithra” Youtube cooking channel along with his 28-year-old wife S. Pavithra – was sentenced to a three-year good behaviour bond of RM8,000 by Sessions Court judge Norashima Khalid on Monday (Jan 11).
Lawyer Mohamad Hafiz Jalaludin, who represented the 29-year-old former estate worker, thanked the court for the decision.
We are relieved that the court has agreed to sentence our client with such an order. We believe Sugu s wife will pay for the bond, he said when met outside the courtroom. ....

Liyana Zawani Mohd Radzi , Raja Permaisuri Bainun , Sugu Pavithra Youtube , Muhammad Shahrul Nizam Mohd , Sessions Court , Hospital Raja Permaisuri Bainun , Norashima Khalid , Mohamad Hafiz Jalaludin , Muhammad Shahrul Nizam Mohd Radi , Ipoh City Icon , Public Prosecutor Liyana Zawani Mohd Radzi , Courts Crime , M Sugu , Sugu Pavithra , S Pavithra , Raja Permaisuri Bainun Hospital , சுகு பவித்ரா வலைஒளி , அமர்வுகள் நீதிமன்றம் , மஹாமட் ஹ்யாஃபிஸ் ஜலாலுடின் , இப்போ நகரம் ஐகான் , நீதிமன்றங்கள் குற்றம் , மீ சுகு , சுகு பவித்ரா , கள் பவித்ரா ,